About
Torx® Software
Torx Software is a cloud-based DMTA (design-make-test-analyze) application which supports hypothesis-driven drug design and facilitates real-time information exchange to streamline your drug discovery process. Torx is a collaboration between Cresset and Elixir Software.
Testimonials from customers
The ability to see progress across projects for design and synthesis helps us work out where there are hold-ups so we can make informed resourcing decisions
Top 10 global pharmaceutical company
Torx has revolutionised the way we communicate & prioritise designs within project teams and with our synthetic chemistry CRO partners. Working across multiple projects and with a range of external partners, we have embedded the software into our workflows to improve chemistry delivery. Torx has enabled increased flexibility in working with our collaborators and improved communication of relative priorities. We can make informed decisions quickly and track delivery of key molecules to rapidly advance our programs.
Associate Director, Medicinal Chemistry, Cambridge Biotech
Torx Make has immediately become integral to Monte Rosa’s informatics ecosystem and is fundamental to the way that chemists work. The integration with in-house databases has provided additional efficiencies for our CRO partners and Monte Rosa chemists, removing manual registration steps. Torx Make readily scales with our expanding requirement to leverage more externalized chemistry.
Bernhard Fasching, Vice President, Chemistry at Monte Rosa
There was a huge time saving in back-and-forth communications. I think we saved 2hrs/week/scientist for a total saving of 40hrs/week or 1 full time equivalent (FTE), plus another 4-6 hrs/week/dept head on coordination, equalling almost another FTE.
R&D IT Manager, San Francisco-based biotech
Torx Make has rapidly become a crucial node in Evariste's chemistry platform and is essential to the way we communicate with CROs. Our virtual model means that efficient interaction with our external chemists is fundamentally important and Torx Make has helped significantly in this regard. We look forward to further expanding our use of the Torx platform as Evariste grows.
Alfie Brennan, Chief Scientific Officer, Evariste
It is easy to identify any productivity bottlenecks, make quick and informed decisions about changes to priorities or assignments, and communicate these updates to team members and CROs. By providing immediate, real-time access to design and synthesis information, Torx ensures that we are investing our resources in the most critical compounds.
Toni Kline, Senior Director of Chemistry at Engine Biosciences
We were relying on emails to exchange information, which ended up either in PDFs buried in a file share or in people’s memory. It was difficult to keep track of who was making what, or to find out if something had been done before, which meant that people at different locations were working on the same target and some compounds were re-proposed unnecessarily. There was also the risk of timelines sliding because an important compound went under the radar and wasn’t worked on in a timely manner.
Director of Informatics, Boston-based biotech
The back of the napkin math for us on ROI (return on investment) was a $60K investment/year for $500K in time savings for scientists to do more high value work.
R&D IT Manager, San Francisco-based biotech
Cresset Software was founded by Dr Andy Vinter in 2002. His ground-breaking research on new virtual screening technology for drug discovery formed the scientific foundation of the company and has underpinned our technical development ever since. Cresset software relies on robust scientific methods that use 3D molecular electrostatics and shape to shed light on the properties and behaviors of chemical structures and, crucially, to understand the key interactions which underpin biological activity.
Computational and medicinal chemists use Cresset's software solutions to create models of how molecules interact with each other, in order to understand which molecules are most likely to create the biological effects that they want. They carry out virtual experiments to discover the likely results of changes to the molecular structure, before choosing which molecules to make and test in the laboratory. Today, chemists in the world’s leading research organizations use Flare™ and Forge™ for structure-based and ligand-based molecule design, while Blaze™ and Spark™ offer leading solutions for virtual screening and bioisostere replacement.
In addition, Cresset Discovery Services offers computational chemistry consulting; helping companies remove roadblocks in their project and giving new ideas about the next best steps for their research.
Elixir Software was launched in 2012 by co-founders Dr Paul Faulder and Dr Martin Harrison with the sole purpose of creating software to improve the efficiency of team work, focussing initially on the scientific R&D community.
Having built a team of software engineers and scientists with a legacy of experience in pharmaceutical and biotech R&D, Elixir created and continue to develop their core technology, iTraX™; a vizually rich, web-based real-time tracking application, used by managers and scientists to better plan, manage and track delivery of work into scientific R&D projects.
Elixir invested significant resource into a configuration of iTraX that created their flagship application chemTraX™ to support the Design-Make-Test-Analyze workflow that underpins the mantra of chemistry teams working towards their next clinical candidate. chemTraX captures design hypotheses and design ideas and facilitates the tracking of compounds through the synthesis cycle whether carried out in-house or with outsourced partners.
chemTraX is a popular addition to the software toolbox of major pharmaceutical companies and smaller biotech companies alike due to its ability to unite disparate and co-located teams onto a single application, and the transparency and efficiency savings that it brings.